Scale-up: the key to process development

Scale-up has been a major component of the research and development activities of practising chemical engineers for many years. Any new process development and transfer to manufacturing has traditionally involved benchscale and pilot plant scale-up activities. Modeling and simulation tools have continued to evolve and their impact on today’s scale-up projects is increasingly significant. This symposium is expected to reflect the diversity of scale-up engineering as practiced in various industries and research laboratories.

Scope

Organization and infrastructure for process development scale-up

  • Technical aspects
  • Economics of scale-up and scale

Modeling and simulation for scale-up

  • Similitude
  • Dimensional analysis
  • First principle modeling

Reactor scaleup

  • Scaleup of stirring in tank reactors
  • Heat exchange in reactor scaleup
  • Fixed bed reactor scaleup
  • Polymerization reactor scaleup

Feed and product quality in scale-up

  • Feed purification
  • In-process and product analysis and quality control

Publication

This symposium will be included in the WCCE8 proceedings.

Organizers

Jonathan Worstell
Principal Scientist
Shell Global Solutions US Inc
Westhollow Technology Center
P.O. Box 1380
Houston, TX 77251-1380
Phone: (281) 544-7907
jon.worstell@shell.com

Joseph Powell
Chief Scientist - Chemical Engineering
Shell Global Solutions US Inc.
Westhollow Technology Center
P.O. Box 1380
Houston, TX 77251
Phone: (281) 544-8976
joe.powell@shell.com

Members of the Scientific Committee

Salvador Aldrett, Shell Global Solutions US Inc., Houston, TX, USA
Jim Thomson, Zeton Inc, Burlington, Ontario, Canada
Sue Degaleesan, Shell Global Solutions US Inc., Houston TX, USA
George Liebermann, Xerox Research Centre of Canada, Mississauga, Ontario, Canada